Method of detecting human cytochrome p4501a2 gene polymorphism

Details Method of detecting human cytochrome p4501a2 gene polymorphism Method of detecting human cytochrome p4501a2 gene polymorphism

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2170052

The present invention provides a method for detecting polymorphism of the human cytochrome P4501A2 (CYP1A2) gene in which substitution at a 2064th base, substitution at a 2640th base, and/or deletion of a -1569th base in a nontranslational region of the human cytochrome P4501A2 gene are/is detected. According to the method of the invention, new types of polymorphism of the CYP1A2 gene can be detected simply and easily with high sensitivity and accuracy, and the method requires only a small amount of a DNA sample.

Procédé de détection de polymorphisme des gènes du cytochrome humain P4501A2 (CYPIA2) selon lequel le remplacement de la 2064ème base, de la 2640ème base et/ou la suppression de -1569ème base survenant dans la région non traduite du gène CYPIA2 peuvent être détectés. Ce procédé permet de détecter de manière pratique, facile avec une grande sensibilité et précision un nouveau polymorphisme des gènes du cytochrome CYHPIA2 à l'aide d'un d'échantillon d'ADN de faible volume.

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