Diagnosis of pre-eclampsia using pigf with pai-1, pai-2 and...

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G01N 33/68 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2427645

The present invention relates to a method of predicting pre-eclampsia (PE). The present invention also relates to a diagnostic kit for performing a method of predicting PE. In particular, the method determining the level of two or more markers selected from placenta growth factor (PIGF), plasminogen activator inhibitor-1 (PAI-1) plasminogen activator inhibitor-2 (PAI-2) and leptin.

La présente invention se rapporte à une méthode permettant de prévoir la pré-éclampsie (PE). Cette invention traite également d'un matériel de diagnostic permettant de mettre en oeuvre la méthode de prévision de la PE. En particulier, cette méthode permet de déterminer le niveau de deux marqueurs ou davantage choisis parmi un facteur de croissance placentaire (PlGF), un inhibiteur de type 1 de l'activateur du plasminogène (PAI-1), un inhibiteur de type 2 de l'activateur du plasminogène (PAI-2), et la leptine.

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