Methods of using and compositions comprising pde4 modulators...

Details Methods of using and compositions comprising pde4 modulators... Methods of using and compositions comprising pde4 modulators...

A - Human Necessities

61

K

A61K 31/496 (2006.01) A61K 31/4035 (2006.01) A61K 31/4409 (2006.01) A61P 31/06 (2006.01)

Patent

CA 2750123

Methods of treating, preventing, and managing tuberculosis and other related disorders are disclosed. The methods comprise the administration of a PDE4 modulator, or a pharmaceutically acceptable salt, solvate, hydrate, clathrate, stereoisomer, or prodrug thereof, optionally in combination with a second active agent and/or other conventional therapies. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in such methods are also disclosed.

L'invention concerne des méthodes pour traiter, prévenir, et gérer la tuberculose et d'autres troubles associés. Les méthodes consistent à administrer un modulateur de PDE4, ou un sel, un solvate, un hydrate, un clathrate, un stéréoisomère, ou un promédicament pharmaceutiquement acceptable correspondant, éventuellement combiné à un second agent actif et/ou à d'autres thérapies classiques. L'invention concerne également des compositions pharmaceutiques, des formes de dosage à une seule unité, et des kits appropriés pour être utilisés dans le cadre de ces méthodes.

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