Virucidal compositions

Details Virucidal compositions Virucidal compositions

A - Human Necessities

61

K

A61K 31/045 (2006.01) A61K 31/047 (2006.01) A61K 47/04 (2006.01) A61K 47/12 (2006.01) A61P 29/00 (2006.01) A61P 31/12 (2006.01) A61P 31/22 (2006.01)

Patent

CA 2439413

A method of inactivating viruses comprises contacting the virus with a virucidally effective amount of a composition consisting essentially of a C1 to C3 monohydroxy alcohol or a C2 to C4 diol and a sufficient amount of an acid to adjust the pH of the composition to below 4.6. Topical administration of the composition is preferred and is effective in treating lesions associated infections by viruses such as herpes simplex. Nasal deliverable forms are effective in treating symptoms due to viruses that cause the common cold. Pharmaceutical compositions for use in the present method are provided.

L'invention concerne un procédé relatif à l'inactivation de virus, qui consiste à mettre le virus en contact avec une quantité virucide efficace de composition essentiellement constituée d'alcool monohydroxy C1 à C3 ou de diol C2 à C4 et une quantité suffisante d'acide permettant d'ajuster le pH de la composition à un niveau inférieur à 4,6. De préférence, on procède à une administration topique de la composition, qui est efficace pour le traitement des lésions associées aux infections provoquées par des virus du type herpès simplex. Les formules destinées à être administrées par voie nasale sont efficaces pour le traitement des symptômes associés aux virus qui engendrent le rhume simple. L'invention concerne également des compositions pharmaceutiques utilisables dans le cadre du procédé décrit.

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