Preparation of 2-amino-6-chloropurine

Details Preparation of 2-amino-6-chloropurine Preparation of 2-amino-6-chloropurine

C - Chemistry, Metallurgy

07

D

C07D 473/40 (2006.01) C07D 473/32 (2006.01)

Patent

CA 2117435

A process for preparing 2-amino-6-chloropurine comprises reacting a 2,9-diacylated derivative of guanine with a chlorinating agent in the presence of a phase transfer catalyst containing chloride ions, and thereafter removing the 9-acyl group and the 2-acyl group by hydrolysis.

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