C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 19/10 (2006.01) C07H 19/20 (2006.01) C07H 21/00 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2357793
The invention concerns a functionalised compound of general formula (I) wherein: W represents a nucleotide analog; L represents a binding group comprising at least four atoms; R¿1? represents a linear or branched alkyl chain. The invention also concerns one said functionalised polynucleotide, one marked polynucleotide, including at least a functionalised compound corresponding to formula (I'). The invention further concerns a method for detecting a target nucleic acid using one said compound.
L'invention concerne un composé fonctionnalisé de formule générale (I): dans laquelle W représente un analogue nucléotidique, L représente un bras de liaison comportant au moins quarte atomes, R¿1? représente une chaîne alkyle, linéaire ou ramifiée, un polynucléotide fonctionnalisé, comprenant au moins undit composé, un polynucléotide fonctionnalisé, marqué, comprenant au moins un composé fonctionnalisé répondant à la formule (I'). Il est décrit un procédé de détection d'un acide nucléique cible utilisant undit composé.
Defranc Eric
Laayoun Ali
Lhomme Jean
Trevisiol Emmanuelle
Bio Merieux
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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