Calcium phosphate cements prepared from silicate solutions

Details Calcium phosphate cements prepared from silicate solutions Calcium phosphate cements prepared from silicate solutions

C - Chemistry, Metallurgy

04

B

C04B 12/02 (2006.01) A61K 6/06 (2006.01) A61L 24/00 (2006.01) A61L 24/02 (2006.01) C04B 14/36 (2006.01) C04B 24/00 (2006.01) C04B 28/34 (2006.01)

Patent

CA 2407115

Methods are provided for producing flowable compositions, e.g. pastes, that set into calcium phosphate products. In the subject methods, dry reactants that include a calcium source and a phosphate source are combined with a solution of a soluble silicate, e.g. sodium silicate, and the combined liquids and solids are mixed to produce the flowable composition. Also provided are the compositions themselves as well as kits for preparing the same. The subject methods and compositions produced thereby find use in a variety of applications, including the repair of hard tissue defects, e.g. bone defects.

L'invention concerne des procédés de production de compositions fluides, à savoir de pâtes, introduites dans des produits de phosphate de calcium. Dans ces procédés, les réactifs secs comprenant une source de calcium et une source de phosphate sont combinés à une solution de silicate soluble, à savoir du silicate de sodium, et les liquides et solides combinés sont mélangés, afin de produire une composition fluide. L'invention concerne également les compositions elles-mêmes, ainsi que des nécessaires destinés à les préparer. Ces procédés et les compositions produites ainsi s'utilisent dans diverses applications, tel que dans la réparation des défauts d'un tissu dur, à savoir des défauts osseux.

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