Diazabicycloalkene derivatives

Details Diazabicycloalkene derivatives Diazabicycloalkene derivatives

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01) A61K 31/495 (2006.01) A61K 31/53 (2006.01) C07D 405/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01) C07D 491/04 (2006.01) C07D 491/052 (2006.01)

Patent

CA 2096067

ABSTRACT OF THE DISCLOSURE A compound of formula (I) possesses excellent potassium channel opening activity and is effective on various diseases arising from contractions of blood vessels, bronchial smooth muscles, etc., for example, ischemic heart diseases exemplified by angina pectoris, asthma, pollakisuria, sequela of subarachnoid hemorrhage, peripheral arterioinfarct, and so on. The compound has potent and long-lasting antihypertensive activity, with the onset of the action being slow, excellent activity in increasing renal blood flow, and high safety, and is therefore particularly useful as an antihypertensive. Image (I) The substituents are as defined in the specifica- tion. - 106 -

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