Plasticized bioerodible controlled delivery system

Details Plasticized bioerodible controlled delivery system Plasticized bioerodible controlled delivery system

A - Human Necessities

61

K

A61K 9/08 (2006.01) A61K 9/00 (2006.01) A61K 9/06 (2006.01) A61K 47/34 (2006.01)

Patent

CA 2153064

A controlled release controlled delivery system comprises a plasticized bioerodible polymer, such as a polyorthoester. Medicament desirably is entrapped in the plasticized polymer. The resulting delivery system is able to release the medicament in a controlled and sustained manner. The formulation is particularly advantageous for use as a once-a-day eyedrop. During preparation, the polymer may be heated to an elevated temperature for a sufficient time to substantially reduce its molecular weight.

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