Compositions and methods for inhibiting white spot syndrome...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/34 (2006.01) A23K 1/17 (2006.01) A61K 35/76 (2006.01) A61P 31/20 (2006.01) C07K 14/01 (2006.01)

Patent

CA 2537995

COMPOSITIONS AND METHODS FOR INHIBITING WHITE SPOT SYNDROME VIRUS (WSSV) INFECTION ABSTRACT OF THE DISCLOSURE The present invention relates to a novel composition useful for inhibiting White Spot Syndrome Virus (WSSV) infection of crustacean animals, particularly those of the genera Penaeus sp. More specifically, the novel composition comprises a polypeptide whose amino acid sequence corresponds to at least a portion of Vp28, a surface protein of WSSV, or an antibody that specifically binds the polypeptide. The polynucleotide sequences encoding the Vp28 polypeptides of the present invention are also disclosed. Further disclosed are methods for using the novel compositions to inhibit WSSV infection in crustacean animals.

L'invention concerne une composition utile pour inhiber l'infection par le virus de la maladie des points blancs chez les crustacés, en particulier du genre Penaeus sp. Plus précisément, ladite composition comprend un polypeptide dont la séquence d'acides aminés correspond au moins à une partie de Vp28, protéine de surface du virus considéré, ou un anticorps qui se lie spécifiquement au polypeptide. On décrit également les séquences polynucléotidiques codant les polypeptides Vp28 considérés. L'invention concerne en outre des procédés relatifs à l'utilisation des compositions décrites pour inhiber l'infection visée chez les crustacés.

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