A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/12 (2006.01) A01H 5/00 (2006.01) A61K 39/29 (2006.01) A61K 48/00 (2006.01) A61P 31/14 (2006.01) C07K 14/10 (2006.01) C12N 7/04 (2006.01) C12N 15/82 (2006.01)
Patent
CA 2412343
A vaccine produced in edible plant and/or animal products, as well as a method of second generation vaccine development through the production of at least one complete structure of a pathogen in a transgenic plant or animal. Preferably, the present invention enables the production of virus-like particles in edible food plants, through the co-expression of a plurality of proteins and/or of a plurality of portions of such proteins. The co-expression of viral structural proteins should enhance the proper presentation of viral related antigens to the human immune system.
L'invention porte sur un vaccin élaboré dans des plantes comestibles ou dans des produits animaux et sur un procédé de réalisation de vaccins de deuxième génération consistant à produire au moins une structure pathogène complète dans une plante ou un animal transgénique. L'invention porte de préférence sur l'élaboration de particules de type viral dans des plantes comestibles par co-expression de plusieurs protéines et/ou de plusieurs de leurs parties. La co-expression de protéines de structure virale devrait améliorer la présentation idoine d'antigènes apparentés aux virus au système immunitaire humain.
Galun Eithan
Galun Esra
Gauss-Mueller Verena
Gilad Mali Ketzinel
Giladi Hilla
Hadasit Medical Research Services And Development Ltd.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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