A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/00 (2006.01) A61K 9/06 (2006.01) A61K 47/02 (2006.01) A61K 47/48 (2006.01)
Patent
CA 2692610
The subject of the present invention is a transdermal preparation containing pharmaceutically active ingredient, wherein the particles of the active ingredient are coated with highly volatile silicones or a mixture thereof, and these coated particles are dispersed in a gel or cream base. The volatile silicone component is hexamethyldisiloxane and/or octamethyltrisiloxane and/or decamethylpentacyclo-siloxane. A further subject of the present invention is a method for the preparation of such pharmaceutical compositions.
La présente invention concerne une préparation transdermique qui contient un ingrédient pharmaceutiquement actif, les particules de l'ingrédient actif étant enduites de silicones hautement volatiles ou d'un mélange de ceux-ci. Ces particules enduites sont dispersées dans une base de gel ou de crème. Le composant de silicone volatil est l'hexaméthyldisiloxane et/ou l'octaméthyltrisiloxane et/ou le décaméthylpentacyclosiloxane. La présente invention concerne également un procédé de préparation de telles compositions pharmaceutiques.
Fazekas Patrik
Mikulasik Endre
Egis Gyogyszergyar Nyilvanosan Mukodo Reszvenytarsasag
Fetherstonhaugh & Co.
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