Treating or preventing extracellular matrix build-up

Details Treating or preventing extracellular matrix build-up Treating or preventing extracellular matrix build-up

C - Chemistry, Metallurgy

07

K

C07K 14/575 (2006.01)

Patent

CA 2558039

A method of treatment for treating, preventing, inhibiting or reducing extracellular matrix build-up in a body tissue or a bodily fluid transport vessel, in a subject, includes administering to a subject in need of such treatment an effective amount of a composition including a peptide agent including amino acid sequence LKKTET, a conservative variant thereof, or a peptide agent that stimulates production of an LKKTET peptide, or a conservative variant thereof, in the tissue.

La présente invention concerne une technique de traitement permettant de traiter, de prévenir, d'inhiber ou de réduire la formation de matrice extracellulaire dans un tissu organique ou dans un vaisseau de transport de liquide organique, chez un sujet, qui consiste à administrer au sujet nécessitant ce traitement une quantité efficace d'une composition comprenant un agent peptidique incluant une séquence d'acide aminé LKKTET, un peptide ou un variant conservateur de celui-ci dans ce tissu.

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