Generating replicating molecules in vivo

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/86 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C12N 15/861 (2006.01)

Patent

CA 2257916

The invention discloses circular and replicating DNA molecules, useful in gene therapy, as well as a particularly efficient method for generating them in situ from a viral vector.

La présente invention concerne des molécules d'ADN circulaires et réplicatives, utilisables en thérapie génique, ainsi qu'une méthode particulièrement efficace pour leur génération in situ à partir d'un vecteur viral.

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