Composition comprising a nsaid and paracetamol

Details Composition comprising a nsaid and paracetamol Composition comprising a nsaid and paracetamol

A - Human Necessities

61

K

A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 31/192 (2006.01) A61K 31/67 (2006.01)

Patent

CA 2623281

A process for producing a granular composition comprising a plurality of solidified melt granules including a non-steroidal anti-inflammatory drug (NSAID) and paracetamol, the process comprising the steps of: (a) forming a melt mixture by mixing a molten NSAID free acid and paracetamol, optionally with one or more excipients; and (b) forming the melt mixture into solidified melt granules.

L'invention concerne un procédé destiné à produire une composition granulaire comprenant une pluralité de granules de fusion solidifiés renfermant un anti-inflammatoire non stéroïdien (AINS) et du paracétamol. Ce procédé consiste (a) à former un mélange de fusion par mélange d'un acide libre d'AINS fondu et de paracétamol, éventuellement avec un ou plusieurs excipients, et (b) à former le mélange de fusion en granules de fusion solidifiés.

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