Synergistic composition of cd4-based protein and anti-hiv-1...

Details Synergistic composition of cd4-based protein and anti-hiv-1... Synergistic composition of cd4-based protein and anti-hiv-1...

C - Chemistry, Metallurgy

07

K

C07K 16/10 (2006.01) A61K 39/42 (2006.01) A61L 2/02 (2006.01) C07K 14/73 (2006.01) C07K 19/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2156421

The invention provides compositions having a carrier, a CD4-based protein and an antibody which specifically binds an epitope on an HIV-1 envelope glycoprotein required for fusion of a CD4-containing membrane with a containing the HIV-1 envelope glycoprotein. The invention also provides methods of using the compositions for treating and/or preventing HIV-1 infection and for decontaminating fluids containing HIV-1.

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