Quinoline as allosteric enhancers of the gaba-b receptors

Details Quinoline as allosteric enhancers of the gaba-b receptors Quinoline as allosteric enhancers of the gaba-b receptors

C - Chemistry, Metallurgy

07

D

C07D 215/18 (2006.01) A61K 31/4738 (2006.01) A61P 25/22 (2006.01) C07D 215/20 (2006.01) C07D 215/38 (2006.01) C07D 401/04 (2006.01) C07D 491/04 (2006.01)

Patent

CA 2586066

The present invention relates to compounds of formula (I) wherein R1 to R6 are as defined as described herein, which compounds are active at the GABAB receptor and can be used for the preparation of medicaments useful in the treatment of CNS disorders comprising anxiety and depression.

La présente invention concerne des composés de la formule (I) dans laquelle R1 à R6 ont la notation définie dans la description, lesquels composés sont actifs au niveau du récepteur GABAB et peuvent être utilisés dans la préparation de médicaments utiles dans le traitement de troubles du système nerveux central CNS notamment de l'angoisse et de la dépression.

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