Release of lipophilic active agents from chewing gum

Details Release of lipophilic active agents from chewing gum Release of lipophilic active agents from chewing gum

A - Human Necessities

61

K

A61K 9/14 (2006.01) A61K 9/00 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01)

Patent

CA 2406552

Methods and compacted powder formulations for delivering a powdered medicament or agent to an individual are provided. The compacted powder formulation includes a medicament or agent. The compacted powder formulation also includes a sufficient amount of a masking agent to allow the consumer to allow at least a portion of the product to dissolve in his or her mouth due to the flavor masking abilities of the compacted powdered oral dosage form. It is believed that by placing the compacted powder formulation into the mouth of the user, the medicament or agent is released, enhancing the absorption of the drug into the systemic system as well as the bioavailability of the drug within the system.

L'invention concerne des procédés et des formulations de poudre compactée pour administrer un médicament ou agent en poudre à un individu. La formulation de poudre compactée comprend un médicament ou un agent. La formulation de poudre compactée comprend également une quantité suffisante d'un agent de masquage pour permettre au consommateur de dissoudre au moins une partie du produit dans sa bouche, grâce aux propriétés de masquage aromatique de la forme de dosage orale en poudre compactée. On pense que lorsque l'on place la formulation de poudre compactée dans la bouche de l'utilisateur, le médicament ou l'agent se diffuse, améliorant ainsi l'absorption du médicament dans le système général, ainsi que la biodisponibilité du médicament à l'intérieur du système.

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