Novel compositions and uses thereof

A - Human Necessities – 61 – K

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Details

A61K 47/12 (2006.01) A61K 47/24 (2006.01) A61K 47/26 (2006.01)

Patent

CA 2714002

The present invention provides structured surfactant systems comprising water and from 0 to saturation of sugar, together with sufficient surfactant to form a structure capable of suspending solids, wherein the surfactant comprises a mixture of: (i) a major portion of at least one sugar ester and/or a triterpenoid glycoside (saponin) having an HLB greater than 10; and (ii) a minor portion of at least one fatty acid and/or lecithin. The invention further provides pharmaceutical compositions comprising a structured surfactant system of the invention and a pharmaceutical or veterinary active ingredient.

L'invention concerne des systèms tensioactifs structurés contenant de l'eau et entre 0 et une saturation de sucre, associés à un tensio-actif suffisant pour former une structure capable de mettre en suspension des solides. Le tensioactif est composé d'un mélange: (i) d'une grande partie d'au moins un ester de sucre et/ou de glycoside triterpénoïde (saponine) présentant un rapport hydrophile-lipophile supérieur à 10; et (ii) une petite partie d'au moins un acide gras et/ou de lécithine. L'invention concerne, de plus, des compositions pharmaceutiques comprenant un système tensio-actif structuré de l'invention et un principe actif pharmaceutique ou vétérinaire.

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