C - Chemistry – Metallurgy – 08 – L
Patent
C - Chemistry, Metallurgy
08
L
C08L 5/08 (2006.01) A61K 47/36 (2006.01) A61K 47/48 (2006.01) C08K 5/00 (2006.01) C08J 3/24 (2006.01)
Patent
CA 2704162
This invention relates to a cross-linkable chitosan composition comprising chitosan having a degree of deacetylation between 30 and 75%, wherein the chitosan is randomly deacetylated, and a cross- linking agent, wherein the molar ratio of the cross- linking agent to chitosan is 0.2: 1 or less based on the number of functional groups in the cross-linking agent and the number of accessible amino groups in the chitosan. The invention also provides a chitosan hydrogel formed therefrom and uses thereof.
La présente invention concerne une composition de chitosane réticulable qui comprend du chitosane dont le degré de désacétylation se situe entre 30 et 75 %, lequel chitosane est aléatoirement désacétylé, et un agent de réticulation, dont le rapport molaire de l'agent de réticulation au chitosane est de 0,2: 1 ou moins, basé sur le nombre de groupes fonctionnels dans l'agent de réticulation et le nombre de groupes amino accessibles dans le chitosane. L'invention concerne également un hydrogel de chitosane formé à partir de la composition et des utilisations de celui-ci.
Riches Mckenzie & Herbert Llp
Viscogel Ab
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