C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 495/04 (2006.01) A61K 31/505 (2006.01) C07D 403/06 (2006.01) C07D 471/04 (2006.01) C07D 471/14 (2006.01) C07D 487/04 (2006.01) C07D 487/14 (2006.01) C07D 491/04 (2006.01) C07D 491/048 (2006.01) C07D 491/14 (2006.01) C07D 491/147 (2006.01) C07D 495/14 (2006.01)
Patent
CA 2211212
The present invention relates to a compound of formula (I) and the pharmaceutically acceptable salts thereof wherein W is a tricyclic heterocyclic ring system; which is an .alpha.-1 adrenergic antagonist and is useful in the treatment of BPH; also disclosed are .alpha.-1 antagonist compositions and a method for antagonizing .alpha.-1 receptors and treating BPH.
La présente invention concerne un composé, ainsi que ses sels acceptables sur le plan pharmaceutique, correspondant à la formule (I) où W est un système de noyau hétérocyclique tricyclique. Ce composé est un antagoniste .alpha.-1 adrénergique utile dans le traitement de l'hyperplasie prostatique bénigne. Cette invention concerne également des compositions à base d'antagoniste .alpha.-1 ainsi qu'un procédé visant à rendre antagonistes des récepteurs .alpha.-1, et utilisé dans le traitement de l'hyperplasie prostatique bénigne.
Altenbach Robert J.
Basha Fatima Z.
Carroll William A.
Drizin Irene
Elmore Steven W.
Abbott Laboratories
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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