Cell display of antibody libraries

Details Cell display of antibody libraries Cell display of antibody libraries

C - Chemistry, Metallurgy

12

N

C12N 5/00 (2006.01) C07K 16/00 (2006.01) C07K 16/46 (2006.01) C12N 7/00 (2006.01) C12N 7/01 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2625619

The present invention relates to a viral vector encoding for a library of antibodies or antibody fragments that are displayed on the cell membrane when expressed in a cell. The present invention provides cells comprising the viral vector nucleic acids and methods of screening the libraries for antibodies or antibody fragments with desired characteristics.

Vecteur viral codant une librairie d'anticorps ou de fragments d'anticorps affichés sur la membrane cellulaire en cas d'expression dans une cellule. Cellules comprenant les acides nucléiques du vecteur viral et procédés d'analyse des librairies à la recherche d'anticorps ou de fragments d'anticorps ayant des caractéristiques souhaitées.

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