Set of means for treating a malignant pathology, an...

Details Set of means for treating a malignant pathology, an... Set of means for treating a malignant pathology, an...

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 35/14 (2006.01)

Patent

CA 2685057

Set of means for treating a malignant pathology, an autoimmune disease or an infectious disease, comprising an effector cell which expresses the Fc.gamma.RIII receptor (CD16) at its surface, and a monoclonal antibody, wherein the affinity of the Fc region of said monoclonal antibody for CD16 is greater than the affinity of the Fc region of polyclonal immunoglobulins for CD16.

Ensemble de moyens pour le traitement d'une pathologie maligne, d'une maladie auto-immune ou d'une maladie infectieuse, comprenant une cellule effectrice qui exprime le récepteur Fc.gamma.RIII (CD16) à sa surface, et un anticorps monoclonal, l'affinité de la région Fc dudit anticorps monoclonal pour le CD16 étant supérieure à l'affinité de la région Fc des immunoglobulines polyclonales pour CD16.

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