Alloantigen testing by binding assay

Details Alloantigen testing by binding assay Alloantigen testing by binding assay

G - Physics

01

N

G01N 33/543 (2006.01) G01N 33/564 (2006.01) G01N 33/569 (2006.01) G01N 33/80 (2006.01)

Patent

CA 2103997

2103997 9312425 PCTABS00023 The presence of alloantigen alleles or antibodies to alloantigen alleles is determined by employing a support to which alloantigen alleles are bound, and combining a specimen which contains either the alloantigen alleles or antibodies to alloantigen alleles with a reagent comprising antibodies to the alloantigen allele(s) of interest. By combining the specimen, reagent and support, and determining the amount of antibody which binds to the support as compared to a negative control, the presence of the alloantigen antigen or anti-alloantigen is related to a reduced amount of antibody binding to the support. The amount of antibody may be determined by any convenient assay.

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