C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/62 (2006.01) A61K 38/28 (2006.01)
Patent
CA 2649235
The present invention relates to novel human insulin derivatives which are soluble at physiological pH values and have a prolonged profile of action. The invention also relates to methods of providing such derivatives, to pharmaceutical compositions containing them, to methods of treating diabetes and hyperglycaemia using the insulin derivatives of the invention and to the use of such insulin derivatives in the treatment of diabetes and hyperglycaemia.
La présente invention concerne de nouveaux dérivés insuliniques humain solubles au pH physiologique et à profil d'action prolongé. L'invention concerne également des procédés de réalisation de tels dérivés, des compositions pharmaceutiques les contenant, des procédés utilisant les dérivés insuliniques de l'invention pour le traitement du diabète et de l'hyperglycémie, et l'utilisation de tels dérivés insuliniques pour le traitement du diabète et de l'hyperglycémie.
Garibay Patrick William
Havelund Svend
Hoeg-Jensen Thomas
Hubalek Frantisek
Jakobsen Palle
Dimock Stratton Llp
Novo Nordisk A/s
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