A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 33/00 (2006.01) A61L 31/10 (2006.01) A61L 33/06 (2006.01) B01D 67/00 (2006.01) C09D 183/10 (2006.01)
Patent
CA 2187616
The biocompatibility of polymeric and metallic articles used in contact with blood can be substantially improved by coating the articles as described. The coating materials are triblock copolymers of the polylactone-polysiloxane-polylactone type. Optimum biocompatibility is provided by a coating of optimum surface concentration. Porous membranes can be coated as described, providing improved biocompatibility of blood oxygenators, hemodialyzers and the like.
On peut sensiblement améliorer la biocompatibilité d'articles polymères et métalliques qui, en cours d'utilisation, se trouvent en contact avec du sang, en les recouvrant d'une couche de revêtement. Les matières de revêtement sont des copolymères triséquencés du type polylactone-polysiloxane-polylactone. On obtient la biocompatibilité optimale avec un revêtement à concentration superficielle optimale. On peut recouvrir de cette manière des membranes poreuses afin d'améliorer les biocompatibilités des oxygénateurs de sang, des hémodialyseurs et autres dispositifs similaires.
Chen Yung-Ming
Edrich Richard A.
Fisher Harold
Forrestal Lloyd
Voorhees Marc
Cobe Laboratories Inc.
Mckay-Carey & Company
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