Aldos as modifiers of the igf pathway and methods of use

Details Aldos as modifiers of the igf pathway and methods of use Aldos as modifiers of the igf pathway and methods of use

C - Chemistry, Metallurgy

12

N

C12N 9/88 (2006.01) C07H 21/04 (2006.01)

Patent

CA 2569046

Human ALDO genes are identified as modulators of the IGF pathway, and thus are therapeutic targets for disorders associated with defective IGF function. Methods for identifying modulators of IGF, comprising screening for agents that modulate the activity of ALDO are provided.

L'invention concerne des gènes ALDO humains qui ont été identifiés comme modulateurs de la voie de signalisation IGF et qui constituent par conséquent des cibles thérapeutiques pour des troubles associés à une fonction IGF déficiente. L'invention porte sur des procédés d'identification de modulateurs de l'IGF, qui consistent à cribler des agents modulant l'activité des gènes ALDO.

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