Method to decrease the rate of polyspermy in ivf

Details Method to decrease the rate of polyspermy in ivf Method to decrease the rate of polyspermy in ivf

A - Human Necessities

61

B

A61B 17/43 (2006.01) A61D 7/00 (2006.01) C12N 5/02 (2006.01)

Patent

CA 2570491

The field of invention generally relates to increasing the efficiency of in vitro fertilization by decreasing the rate of polyspermy. One aspect of the invention provides a method of reducing polyspermy in in vitro fertilization by forming an in vitro fertilization mixture that contains osteopontin, oocytes, and sperm, and allowing fertilization of the oocyte by sperm. Another aspect of the invention provides an aqueous mixture for in vitro fertilization that contains osteopontin, oocytes, and sperm.

La présente invention concerne d'une manière générale l'augmentation de l'efficacité de la fécondation in vitro (FIV) par diminution du taux de polyspermie. Un aspect de cette invention concerne une technique de réduction de la polyspermie dans une fécondation in vitro par la formation d'un mélange de fécondation in vitro qui contient de l'ostéopontine, des ovocytes et du sperme et à permettre la fécondation de l'ovocyte par le sperme. Un autre aspect de cette invention concerne un mélange aqueux pour fécondation in vitro qui contient de l'ostéopontine, des ovocytes et du sperme.

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