Conformationally constrained analogs useful as antidiabetic...

Details Conformationally constrained analogs useful as antidiabetic... Conformationally constrained analogs useful as antidiabetic...

C - Chemistry, Metallurgy

07

D

C07D 413/12 (2006.01) A61K 31/42 (2006.01) A61K 31/422 (2006.01) A61K 31/445 (2006.01) A61K 31/454 (2006.01) A61K 31/55 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) C07D 403/02 (2006.01) C07D 413/02 (2006.01) C07D 413/06 (2006.01) C07D 413/10 (2006.01)

Patent

CA 2449006

Compounds are provided which have the structure wherein Q is C or N, X1 is C or N, and R1, R2, R2a, R2, R2c, R3, Y, A, m, n, X2, X3 and X4 are as defined herein, which compounds are useful as antidiabetic, hypolipidemic, and antiobesity agents.

L'invention concerne des composés présentant la structure suivante: [ ], dans laquelle Q représente C ou N, X¿1? représente C ou N et R?1¿, R?2¿, R?2a¿, R?2b¿, R?2c¿, R?3¿, Y, A, m, n, X¿2?, X¿3? et X¿4? sont tels que définis dans la description. Ces composés sont utilisés en tant qu'agents antidiabétiques, hypolipémiants et en tant qu'agents contre l'obésité.

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