Methods for using anti-muc18 antibodies

Details Methods for using anti-muc18 antibodies Methods for using anti-muc18 antibodies

A - Human Necessities

61

K

A61K 39/395 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2471936

The present invention relates generally to the generation and characterization of anti-MUC18 monoclonal antibodies. The invention further relates to the use of such anti-MUC18 antibodies in the diagnosis and treatment of disorders associated with increased activity of MUC18, in particular, tumors, such as melanomas.

Cette invention se rapporte d'une façon générale à la production et à la caractérisation d'anticorps monoclonaux anti-MUC18. Cette invention concerne en outre l'utilisation de ces anticorps anti-MUC18 dans le diagnostic et le traitement des affections associées à une activité accrue de MUC18, en particulier les tumeurs, telles que les mélanomes.

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