Modulation of zinc levels to improve tissue properties

A - Human Necessities – 61 – K

Patent

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A61K 33/32 (2006.01) A61F 2/06 (2006.01) A61K 31/315 (2006.01) A61K 31/555 (2006.01) A61K 31/60 (2006.01) A61K 31/66 (2006.01)

Patent

CA 2503489

Methods of altering properties of tissues, by providing an effective modifying amount of zinc, which may be in the form of zinc ions. This is accomplished through the use of topical compositions containing one or more zinc-containing components such as salts and/or other zinc compounds or complexes, particularly zinc acetate. Altering properties of tissues includes increasing or decreasing fatty tissue, increasing or decreasing epidermal thickness, increasing elastin content, and preventing or treating gum regression or atrophy. Also disclosed is the provision of a contact lens coated with a zinc- containing material, to improve vision by increasing elastin content of the lens of the eye through release of zinc ions.

La présente invention a trait à des procédés de modification des propriétés tissulaires, par la réalisation d'une modification efficace de la quantité de zinc, pouvant être sous la forme d'ions de zinc. Cela est réalisé par l'utilisation de compositions topiques contenant un ou des constituants contenant du zinc tels que des sels et/ou d'autres composés ou complexes de zinc, notamment d'acétate de zinc. La modification des propriétés tissulaires comprend l'accroissement ou la diminution de tissu gras, l'accroissement ou la diminution de l'épaisseur épidermique, l'accroissement du contenu d'élastine, et la prévention ou le traitement de la régression ou l'atrophie de la gencive. L'invention à également trait à la réalisation d'un verre de contact revêtu d'un matériau contenant du zinc, pour l'amélioration de la vision par l'accroissement de contenu d'élastine du cristallin de l'oeil par la libération d'ions de zinc.

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