Chemical functionalization of polymers

C - Chemistry – Metallurgy – 08 – F

Patent

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Details

C08F 8/30 (2006.01) A61K 47/48 (2006.01) A61K 51/06 (2006.01) C07K 17/06 (2006.01) C07K 17/08 (2006.01) C12N 11/06 (2006.01) C12N 11/08 (2006.01) G01N 33/531 (2006.01) G03F 7/012 (2006.01)

Patent

CA 2158550

Methods for covalently modifying polymeric substances, and various so modified polymers, are disclosed. The methods require a functionalizing reagent comprising molecules each having a nitrenogenic group and a functionalizing group. The functionalizing reagent molecules arc brought into reactive proximity to the polymer molecules and exposed to a reaction-energy source such as photons, electrons, or heat, which converts the nitrenogenic groups to nitrene intermediates that covalently react with -CH, -NH, -OH, -C=C-, C-C, and other groups to cause nitrene addition or insertion of the funtionalizing groups to the polymer molecules. Functionalization can be via a one- or multiple-stage process.

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