C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 38/22 (2006.01) A61K 38/45 (2006.01) A61K 38/51 (2006.01) A61K 39/395 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 9/12 (2006.01) C07K 14/47 (2006.01) C07K 14/58 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C07K 16/26 (2006.01) C07K 16/28 (2006.01) C07K 16/40 (2006.01) C07K 16/44 (2006.01) C12N 9/10 (2006.01) C12N 9/88 (2006.01) C12N 15/52 (2006.01) C12N 15/54 (2006.01) C12Q 1/68 (2006.01) G01N 33/50
Patent
CA 2343939
The present invention discloses genes whose expression is modulated in SHR- rats, which is an animal model for human metabolic X syndrome. Also disclosed are genes whose gene products are altered in SHR animals compared to control animals. The invention further discloses methods of diagnosing or treating conditions associated with metabolic X syndrome using these genes and gene products.
La présente invention concerne des gènes dont l'expression est modulée chez le rat spontanément hypertendu (SHR), animal modèle du syndrome X métabolique humain. L'invention concerne aussi des gènes dont les produits géniques, en comparaison avec des animaux témoins, sont altérés chez des animaux SHR. L'invention concerne en outre des méthodes de diagnostic ou de traitement associées au syndrome X métabolique à l'aide de ces gènes et produits géniques.
Curagen Corporation
Everitt Peter R.
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