Method for alleviating keratoconjunctivitis sicca

Details Method for alleviating keratoconjunctivitis sicca Method for alleviating keratoconjunctivitis sicca

A - Human Necessities

61

K

A61K 31/165 (2006.01) A61K 31/167 (2006.01) A61K 31/56 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2644733

An improved method of increasing tear production is by intranasally administering a therapeutically effective amount of a capsaicinoid compound to patients with deficient tear production. Optional incorporation into the intranasal formulation of a topical corticosteroid or topical anesthetic compound is used to reduce transient nasal stinging and burning which may sometimes accompany intranasal administration of capsaicinoids.

L'invention porte sur un procédé amélioré pour augmenter la production de larmes par administration intranasale d'une quantité thérapeutiquement efficace d'un composé capsaicinoïde à des patients ayant une production de larmes déficiente. Une incorporation facultative dans la formulation intranasale d'un corticostéroïde topique ou d'un composé anesthésique topique est utilisée pour réduire la sensation urticante et brûlante nasale transitoire qui peut parfois accompagner l'administration intranasale des capsaicinoïdes.

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