Prilocaine and hydrofluorocarbon aerosol preparations

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/12 (2006.01) A61K 9/72 (2006.01) A61K 31/16 (2006.01) A61K 31/165 (2006.01) A61K 31/167 (2006.01) A61K 31/245 (2006.01) A61K 31/435 (2006.01) A61K 31/445 (2006.01)

Patent

CA 2215680

Prilocaine base, in liquid and micro rod crystal form, can be solubilized within hydrofluorocarbon propellants to produce a stable, oily liquid. The prilocaine base can be used to solubilize additional medicaments within hydrofluorocarbon propellants that are not ordinarily soluble. The combination of prilocaine base and hydrofluorocarbon propellant can be used as an aerosolized spray to provide topical anesthesia.

La prilocaïne basique, sous forme liquide et sous forme de cristaux en microbâtonnets, peut être solubilisée dans des agents de propulsion aux hydrofluorocarbures pour donner un liquide huileux et stable. La prilocaïne basique peut être utilisée pour solubiliser, dans des agents de propulsion de ce genre, des médicaments additionnels qui, habituellement, ne sont pas solubles. L'association de prilocaïne basique et d'un agent de propulsion à l'hydrofluorocarbure peut être utilisée comme brouillard sous forme d'aérosol, pour produire une anesthésie topique.

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