A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4025 (2006.01) A61K 31/337 (2006.01) A61K 31/704 (2006.01) A61K 31/7068 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2687204
A novel pharmaceutical combination comprising a cytotoxic antineoplastic agent selected from a group consisting of paclitaxel, docetaxel, doxorubicin or gemcitabine or a pharmaceutically acceptable salt thereof and at least one cyclin dependent kinase (CDK) inhibitor; wherein the said combination exhibits synergistic effects when used in the treatment of cancer. The invention also relates to a method for the treatment of cancer, using a therapeutically effective amount of the said combination.
L'invention concerne une nouvelle combinaison pharmaceutique comportant un agent antinéoplastique cytotoxique choisi dans un groupe constitué par le paclitaxel, le docétaxel, la doxorubicine ou la gemcitabine ou un sel acceptable du point de vue pharmaceutique de ceux-ci, et au moins un inhibiteur de kinase dépendant de la cycline (CDK); ladite combinaison présentant des effets synergiques lorsqu'elle est utilisée dans le traitement du cancer. L'invention concerne également un procédé pour le traitement du cancer, à l'aide d'une quantité efficace du point de vue thérapeutique de ladite combinaison.
Joshi Kalpana
Khanwalkar Harshal
Rathos Maggie
Sharma Somesh
Piramal Life Sciences Limited
Riches Mckenzie & Herbert Llp
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