Assays for detection of antibodies to lysosomal enzymes

Details Assays for detection of antibodies to lysosomal enzymes Assays for detection of antibodies to lysosomal enzymes

G - Physics

01

N

G01N 33/50 (2006.01)

Patent

CA 2644343

The present invention relates to methods for screening body fluids or tissues for antibodies, including neutralizing and isotype-specific antibodies, against lysosomal enzymes administered as part of enzyme replacement therapy.

La présente invention concerne des procédés de criblage de liquides ou tissus organiques à la recherche d'anticorps, y compris d'anticorps neutralisants et spécifiques d'isotypes, dirigés contre des enzymes lysosomales administrées dans le cadre d'une thérapie de remplacement enzymatique.

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