Slm-1 and slm-2: novel sam68-like mammalian proteins

Details Slm-1 and slm-2: novel sam68-like mammalian proteins Slm-1 and slm-2: novel sam68-like mammalian proteins

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/48 (2006.01)

Patent

CA 2265217

The present invention relates to two Sam68-like mammalian proteins, namely SLM-1 and SLM-2, and nucleic acid molecules encoding the same. The invention also relates to expression vectors and cells capable of expressing said proteins and antibodies capable of specifically binding to said proteins. Kits for the assay of tyrosine kinase activity are discussed which may be used to determine whether or not a cell is cancerous. The present invention further relates to transgenic animals such as "knockout mice" Knockout mice may be used to study the effect of test compounds on SLM-1 or SLM-2 deficiency.

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