A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/01 (2006.01) A61K 38/03 (2006.01) A61K 38/04 (2006.01) A61P 9/00 (2006.01) A61P 11/00 (2006.01) A61P 17/00 (2006.01) A61P 25/00 (2006.01) A61P 31/12 (2006.01) A61P 37/00 (2006.01)
Patent
CA 2725545
The present invention refers to the use of protein kinase inhibitors and more specifically to the use of inhibitors of the protein kinase c-Jun amino terminal kinase, JNK inhibitor sequences, chimeric peptides, or of nucleic acids encoding same as well as pharmaceutical compositions containing same, for the treatment of various diseases or disorders strongly related to JNK signaling, wherein these diseases or disorders are selected from autoimmune disorders, cardiovascular diseases, cancerous diseases, diabetes, including diabetes type 1 or type 2, inflammatory diseases, hair loss, including Alopecia areata, diseases of the lung, neuronal or neurodegenerative diseases, diseases of the liver, diseases of the spine, diseases of the uterus, viral infectious diseases and depressive disorders.
La présente invention a pour objet lutilisation dinhibiteurs de protéine kinases et plus spécifiquement lutilisation dinhibiteurs de la protéine kinase c-Jun amino-terminale, de séquences inhibitrices de JNK, de peptides chimériques ou dacides nucléiques codant pour ceux-ci ainsi que des compositions pharmaceutiques les renfermant, pour le traitement de diverses maladies ou de divers troubles fortement associés à la signalisation de JNK, où ces maladies ou ces troubles sont choisis parmi des troubles auto-immuns, des maladies cardiovasculaires, des maladies cancéreuses, le diabète, y compris le diabète de type 1 ou de type 2, des maladies inflammatoires, la perte des cheveux, y compris la pelade, des maladies du poumon, des maladies neuronales ou neurodégénératives, des maladies du foie, des maladies du rachis, des maladies de lutérus, des maladies infectieuses virales et des troubles dépressifs.
Kirby Eades Gale Baker
Xigen S.a.
LandOfFree
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