Production of a directly compressible tabletting aid

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/10 (2006.01) A61K 47/26 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2306508

The invention relates to directly compressible tabletting aids with a xylitol content of more than 90% by weight and a content of at least one other polyol of less than 10% by weight, which are produced by co-spray drying or co-fluidized bed granulation. The invention further relates to compositions, formulations and solid forms or compacts which comprise a tabletting aid according to the invention, and to a process for producing the tabletting aids according to the invention.

L'invention concerne des auxiliaires d'agglomération directement compressibles, contenant plus de 90 % en poids de xylite et moins de 10 % en poids d'au moins un autre polyol. Lesdits auxiliaires d'agglomération sont obtenus par co-séchage par pulvérisation et par co-granulation en lit fluidisé. Cette invention concerne en outre des compositions, des formulations et des formes galéniques solides et des comprimés, qui contiennent un auxiliaire d'agglomération obtenu selon l'invention, ainsi qu'un procédé permettant de préparer lesdits auxiliaires d'agglomération.

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