Solid pharmaceutical formulation

Details Solid pharmaceutical formulation Solid pharmaceutical formulation

A - Human Necessities

61

K

A61K 47/36 (2006.01) A61K 9/14 (2006.01) A61K 31/4709 (2006.01) A61K 45/00 (2006.01) A61P 7/02 (2006.01)

Patent

CA 2567400

This invention provides a solid pharmaceutical formulation having high physical strength and further having excellent drug release properties and digestibility of excipients when administered, which comprises (a) an active medical ingredient and (b) a pre-gelatinized starch in an amount of 10 to 90 % by weight, said pre-gelatinized starch being prepared by pre-gelatinizing a cheap and stable usual starch during the procedure for formulation. This invention also provides a method for preparing the solid pharmaceutical formulation.

Cette invention fournit une préparation pharmaceutique solide ayant une force physique élevée et d'excellentes propriétés de libération médicamenteuse et digestibilité d'excipients lors de son administration, comprenant (a) un ingrédient médical actif et (b) un amidon pré-gélatinisé en quantité de 10 à 90 % en poids, cet amidon pré-gélatinisé étant préparé en pré-gélatinisant un amidon de qualité courante pendant la procédure de préparation. Cette invention fournit aussi une méthode pour préparer la préparation pharmaceutique solide.

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