Vaccine for house dust mite allergen using naked plasmid dna

Details Vaccine for house dust mite allergen using naked plasmid dna Vaccine for house dust mite allergen using naked plasmid dna

A - Human Necessities

61

K

A61K 31/70 (2006.01) A61K 39/35 (2006.01) A61P 11/06 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2362928

Vaccination with the DNA encoding T-cell epitopes to the house dust mite Dermatophagoides pteronyssimus (Der p) and Dermatophagoides farinae (Der f) were effective in the inhibition of the allergen induced IgE synthesis. Gene therapy using T-cell epitope encoding DNA is useful in combating allergic disease.

La présente invention concerne un vaccin à ADN codant pour les épitopes de lymphocyte T contre les acariens détriticoles Dermatophagoides pteronyssimus (Der p) et Dermatophagoides farinae (Der f). Ce vaccin est efficace dans l'inhibition de la synthèse d'IgE induite par l'allergène. La thérapie génique utilisant l'ADN codant pour les épitopes de lymphocyte T sert à combattre les maladies allergiques.

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