Methods to identify evolutionarily significant changes in...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/29 (2006.01) A01H 5/00 (2006.01) C07K 14/415 (2006.01) C12N 5/04 (2006.01) C12N 15/10 (2006.01) C12N 15/82 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2473555

The present invention provides methods for identifying polynucleotide and polypeptide sequences which may be associated with commercially or aesthetically relevant traits in domesticated plants or animals. The methods employ comparison of homologous genes from the domesticated organism and its ancestor to identify evolutionarily significant changes and evolutionarily neutral changes. Sequences thus identified may be useful in enhancing commercially or aesthetically desirable traits in domesticated organisms or their wild ancestors.

La présente invention concerne des méthodes permettant d'identifier des séquences de polynucléotides et de polypeptides qui peuvent être associées à des caractéristiques importantes commercialement ou esthétiquement chez des plantes ou des animaux domestiqués. Les méthodes utilisent une comparaison de gènes homologues provenant de l'organisme domestiqué et de son progéniteur pour identifier des modifications importantes sur le plan évolutionnaire et des modifications neutres sur le plan évolutionnaire. Les séquences ainsi identifiées peuvent être utilisées dans l'amélioration de caractéristiques souhaitables commercialement ou esthétiquement chez des organismes domestiqués ou leurs progéniteurs sauvages.

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