Dna encoding cephamycin biosynthesis late enzymes

Details Dna encoding cephamycin biosynthesis late enzymes Dna encoding cephamycin biosynthesis late enzymes

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) C12N 9/02 (2006.01) C12N 9/10 (2006.01) C12N 15/53 (2006.01) C12P 35/06 (2006.01)

Patent

CA 2188257

DNA encoding the late enzymes involved in the synthesis of the antibiotic cephamycin have been isolated and purified. The particular enzymes are involved in the late steps of cephamycin biosynthesis. These DNA's have been sequenced and cloned into recombinant expression vectors for their recombinant expression in host cells. The DNA's, vectors containing them and recombinant host cells which express them are useful for the production of antibiotics.

Les ADN codant les enzymes tardifs participant à la synthèse des antibiotiques de la famille des céphamycines ont été isolés et purifiés. Ces enzymes particuliers participent aux dernières phases de la biosynthèse des céphamycines. Ces ADN ont été séquencés et clonés sous forme de vecteurs d'expression de recombinaison permettant leur expression de recombinaison dans des cellules hôtes. Les ADN, les vecteurs les contenant et les cellules hôtes de recombinaison les exprimant sont utiles pour la production d'antibiotiques.

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