C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 1/19 (2006.01) A61K 39/395 (2006.01) C07K 16/00 (2006.01) C07K 16/22 (2006.01) C07K 16/24 (2006.01) C07K 16/28 (2006.01) C12N 1/13 (2006.01) C12N 1/15 (2006.01) C12N 15/09 (2006.01) C12N 15/79 (2006.01) C12P 21/08 (2006.01)
Patent
CA 2590441
The present invention relates to immunoglobulin glycoprotein compositions having predominant N-glycan structures on an immunoglobulin glycoprotein which confer a specific effector function. Additionally, the present invention relates to pharmaceutical compositions comprising an antibody having a particular enriched N-glycan structure, wherein said N-glycan structure is GalGlcNAcMan5GlcNAc2.
l'invention concerne des compositions de glycoprotéines d'immunoglobulines présentant des structures à N-glycane prédominant sur une glycoprotéine d'immunoglobuline, ce qui leur confère une fonction d'effecteur spécifique. De plus, l'invention concerne des compositions pharmaceutiques comprenant un anticorps présentant une structure particulière enrichie en N-glycane, ladite structure N-glycane étant GalGlcNAcMan5GlcNAc2.
Gerngross Tillman U.
Li Huijuan
Wildt Stefan
Glycofi Inc.
Gowling Lafleur Henderson Llp
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