Synthetic antigens for cd1-restricted immune responses

Details Synthetic antigens for cd1-restricted immune responses Synthetic antigens for cd1-restricted immune responses

A - Human Necessities

61

K

A61K 39/00 (2006.01) A61K 39/04 (2006.01) A61K 39/385 (2006.01)

Patent

CA 2302155

Synthetic antigens which comprise hydrophobic and hydrophilic components are provided for inducing CD1-restricted (T) cell-responses in mammals. Further provided are methods for using these antigens and compositions which are combinations of CD1-recognized synthetic antigens, additional antigens, adjuvants and other substances that induce immune responses.

La présente invention concerne des antigènes synthétiques comprenant des composants hydrophobes et hydrophiles qui permettent de provoquer une réponse des cellules T limitée aux CD1 chez les mammifères. L'invention concerne également des procédés d'utilisation de ces antigènes et de compositions qui constituent des combinaisons d'antigènes synthétiques reconnus par les CD1, d'antigènes supplémentaires, d'adjuvants et d'autres substances provoquant une réponse immunitaire.

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