Method of determining type specific antibodies to herpes...

G - Physics – 01 – N

Patent

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G01N 33/577 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2081888

2081888 9117443 PCTABS00008 This enclosure concerns a method of serotyping antibodies to HSV 2 or 1 or in a sample suspected to contain HSV antibodies which comprises: a) reacting the sample and at least one monoclonal antibody specific for HSV-2 or HSV-1 glycoprotein G with an antigen wherein said monoclonal antibody is not susceptible to heterologous blocking; and b) determining whether antibody binding has occurred. The serotyping method of the disclosure can be done in a variety of formats such as sequential or simultaneous. In another embodiment, this disclosure concerns kits for serotyping antibodies to HSV-1 and HSV-2.

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