Antibiotic n-acetylbenanomicin b, and the production and...

Details Antibiotic n-acetylbenanomicin b, and the production and... Antibiotic n-acetylbenanomicin b, and the production and...

C - Chemistry, Metallurgy

07

H

167/184, 260/208

C07H 15/252 (2006.01) A61K 31/70 (2006.01) C07H 15/244 (2006.01)

Patent

CA 2007145

As a new compound is now provided N-acetylbenanomicin B which is useful as an antifungal agent and also as antiviral agent for inhibiting infection of human T-cell with HIV, namely a virus causative of acquired human immunodeficiency syndrome. N-acetylbenanomicin B may be prepared by acetylation of 4"-amino group of benanomicin B which is fermentatively produced by a new microorganism, MH193-16F4 strain of actinomycetes.

Nouveau composé de N-acétylbenanomicine B utile comme agent antifongique et comme agent antiviral pour inhiber l'infection des cellules-T humaines par le VIH, soit le virus à l'origine du syndrome d'immunodéficience acquise humaine. N-acétylbenanomicine B peut être préparé par acétylation du groupement 4Õ-amino de benanomicine B produit par fermentation par un nouveau microorganisme, la souche MH193-16F4 des actinomycètes.

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