Process for the isomerization of semicarbazone compounds

C - Chemistry – Metallurgy – 07 – B

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C07B 57/00 (2006.01) C07C 281/14 (2006.01)

Patent

CA 2727320

The present invention relates to a process for the isomerization of the Z- isomer I-Z of a semicarbazone compound of the general formula (I) into its E-isomer I-E wherein the variables in formula (I) have the meanings as defined in the description said process comprising reacting the Z-isomer I-Z or a mixture of the stereoisomers I-Z and I-E in the presence of at least one organic acid.

La présente invention concerne un procédé pour lisomérisation du Z-isomère I-Z dun composé de semicarbazone de la formule générale (I) en son E-isomère I-E, les variables dans la formule (I) ayant les significations telles que définies dans la description et le procédé consistant à faire réagir Z-isomère I-Z ou un mélange des stéréoisomères I-Z et I-E en présence d'au moins un acide organique.

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