C - Chemistry – Metallurgy – 07 – B
Patent
C - Chemistry, Metallurgy
07
B
C07B 57/00 (2006.01) C07C 269/04 (2006.01) C07C 271/22 (2006.01) C07C 329/06 (2006.01) C07D 207/46 (2006.01) C12P 41/00 (2006.01)
Patent
CA 2706575
Methods of enzymatically resolving acyloxyalkyl thiocarbonates useful in the synthesis of acyloxyalkyl carbamates are disclosed. These carbamates can be coupled to drugs containing amines such as R-baclofen or S-pregabalin.
La présente invention a pour objet des procédés de résolution des énantiomères de thiocarbonates d'acyloxyalkyle utilisés dans la synthèse de précurseurs de carbamates d'acyloxyalkyle.
Gallop Mark A.
Ludwikow Maria J.
Peng Ge
Raillard Steven P.
Yao Fenmei
Fetherstonhaugh & Co.
Xenoport Inc.
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